ITS, '''it's or its''' can mean:
"its", the possessive adjective and possessive pronoun form of the personal pronoun it
"it's", a contraction of "it is" or "it has"
The It's man, a man with torn clothes and unkempt beard who appeared at the beginning of episodes of ''Monty Python's Flying Circus''
;Art
International Typographic Style, a graphic design style developed in Switzerland in the 1950s
;Computing
Incompatible Timesharing System, a computer operating system
Internet technical support, the people you call to repair your Internet connection
Intelligent tutoring system, an artificial intelligence system used for tutoring
Issue tracking system, computer software packages that manage and maintain lists of issues, as needed by an organization
Information Technology Services, a generic name for a computer support department
SAP Internet Transaction Server
iTunes Store
Internationalization Tag Set, a W3C recommendation for internationalizing XML
;Dance
Improv Tribal Style Belly Dance, a sub-genre of Tribal Style Belly Dance
;Education
Instructional Technology Specialist, a person who works with teachers and students to help them integrate instructional or educational technology into teaching and learning environments
Institute of Technology, Sligo, Ireland
Institut Teknologi Sepuluh Nopember, in Surabaya, Indonesia
Intelligent tutoring system, an artificial intelligence system used for tutoring
;Fashion
ITS International Talent Support, an international fashion, accessories and photo competition
;Music
In the Shadows, a song by Finnish band The Rasmus
;Organizations
Islamic Thinkers Society
International Thespian Society, an honorary organization for high school and middle school theatre students
International Tracing Service
Identity, Tradition, Sovereignty, a political grouping in the European Parliament
;Science and engineering
Integrated Truss Structure, a component of the International Space Station
Intelligent Transportation System, application of IT to transportation
ITS-90, or International Temperature Scale, which provides the defining points for temperature
Internal transcribed spacer, a section of DNA located within a set of ribosomal genes
;Other
Integrated/Embedded Mission Training Systems by Simlat
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